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Kronologisk publiceringslista
2018 The association between multiple sclerosis and pain medications. Burkill S, Montgomery S, Kockum I, Piehl F, Strid P, Hillert J, Alfredsson L, Olsson T, Bahmanyar S. Pain. 2018 Oct 29. doi: 10.1097/j.pain.0000000000001429. [Epub ahead of print] Mowry EM, Hedström AK, Gianfrancesco MA, Shao X, Schaefer CA, Shen L, Bellesis KH, Briggs FBS, Olsson T, Alfredsson L, Barcellos LF. Mult Scler Relat Disord. 2018 Aug;24:135-141. doi: 10.1016/j.msard.2018.06.009. Epub 2018 Jun 23. Organic solvents and MS susceptibility: Interaction with MS risk HLA genes. Hedström AK, Hössjer O, Katsoulis M, Kockum I, Olsson T, Alfredsson L. Neurology. 2018 Jul 31;91(5):e455-e462. doi: 10.1212/WNL.0000000000005906. Epub 2018 Jul 3. Association of Pre-Disease Body Mass Index With Multiple Sclerosis Prognosis. Manouchehrinia A, Hedström AK, Alfredsson L, Olsson T, Hillert J, Ramanujam R. Front Neurol. 2018 May 11;9:232. doi: 10.3389/fneur.2018.00232. eCollection 2018. Lifestyle and Environmental Factors in Multiple Sclerosis. Alfredsson L, Olsson T. Cold Spring Harb Perspect Med. 2018 May 7. pii: a028944. doi: 10.1101/cshperspect.a028944. [Epub ahead of print] 2017 Marabita F, Almgren M, Sjöholm LK, Kular L, Liu Y, James T, Kiss NB, Feinberg AP, Olsson T, Kockum I, Alfredsson L, Ekström TJ, Jagodic M. Sci Rep. 2017 Nov 6;7(1):14589. doi: 10.1038/s41598-017-14788-w. Erratum in: Sci Rep. 2018 Mar 7;8(1):4340. Genetic risk factors for pediatric-onset multiple sclerosis. Gianfrancesco MA, Stridh P, Shao X, Rhead B, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Schaefer C, Barcellos LF, Waubant E; Network of Pediatric Multiple Sclerosis Centers. Mult Scler. 2017 Oct 1:1352458517733551. doi: 10.1177/1352458517733551. [Epub ahead of print] Amato MP, Derfuss T, Hemmer B, Liblau R, Montalban X, Soelberg Sørensen P, Miller DH; 2016 ECTRIMS Focused Workshop Group. Mult Scler. 2017 Jan 6:1352458516686847. doi: 10.1177/1352458516686847. [Epub ahead of print] The interaction between smoking and HLA genes in multiple sclerosis: replication and refinement. Hedström AK, Katsoulis M, Hössjer O, Bomfim IL, Oturai A, Sondergaard HB, Sellebjerg F, Ullum H, Thørner LW, Gustavsen MW, Harbo HF, Obradovic D, Gianfrancesco MA, Barcellos LF, Schaefer CA, Hillert J, Kockum I, Olsson T, Alfredsson L. Eur J Epidemiol. 2017 Oct;32(10):909-919. doi: 10.1007/s10654-017-0250-2. Epub 2017 Jun 8. Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS. Gianfrancesco MA, Stridh P, Rhead B, Shao X, Xu E, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Bäärnhielm M, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Metayer C, Schaefer C, Barcellos LF, Waubant E; Network of Pediatric Multiple Sclerosis Centers. Neurology. 2017 Apr 25;88(17):1623-1629. doi: 10.1212/WNL.0000000000003849. Epub 2017 Mar 29. Gianfrancesco MA, Glymour MM, Walter S, Rhead B, Shao X, Shen L, Quach H, Hubbard A, Jónsdóttir I, Stefánsson K, Strid P, Hillert J, Hedström A, Olsson T, Kockum I, Schaefer C, Alfredsson L, Barcellos LF. Am J Epidemiol. 2017 Feb 1;185(3):162-171. doi: 10.1093/aje/kww120. Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis. Olsson T, Barcellos LF, Alfredsson L. Nat Rev Neurol. 2017 Jan;13(1):25-36. doi: 10.1038/nrneurol.2016.187. Epub 2016 Dec 9. Review. 2016 Parsa R, Lund H, Tosevski I, Zhang XM, Malipiero U, Beckervordersandforth J, Merkler D, Prinz M, Gyllenberg A, James T, Warnecke A, Hillert J, Alfredsson L, Kockum I, Olsson T, Fontana A, Suter T, Harris RA. Glia. 2016 Nov;64(11):1925-37. doi: 10.1002/glia.23033. Epub 2016 Aug 1. Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk. Rhead B, Bäärnhielm M, Gianfrancesco M, Mok A, Shao X, Quach H, Shen L, Schaefer C, Link J, Gyllenberg A, Hedström AK, Olsson T, Hillert J, Kockum I, Glymour MM, Alfredsson L, Barcellos LF. Neurol Genet. 2016 Sep 13;2(5):e97. doi: 10.1212/NXG.0000000000000097. eCollection 2016 Oct. Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies. George MF, Briggs FB, Shao X, Gianfrancesco MA, Kockum I, Harbo HF, Celius EG, Bos SD, Hedström A, Shen L, Bernstein A, Alfredsson L, Hillert J, Olsson T, Patsopoulos NA, De Jager PL, Oturai AB, Søndergaard HB, Sellebjerg F, Sorensen PS, Gomez R, Caillier SJ, Cree BA, Oksenberg JR, Hauser SL, D'Alfonso S, Leone MA, Martinelli Boneschi F, Sorosina M, van der Mei I, Taylor BV, Zhou Y, Schaefer C, Barcellos LF. Neurol Genet. 2016 Aug 4;2(4):e87. doi: 10.1212/NXG.0000000000000087. eCollection 2016 Aug. Environmental factors and their interactions with risk genotypes in MS susceptibility. Hedström AK, Alfredsson L, Olsson T. Curr Opin Neurol. 2016 Jun;29(3):293-8. doi: 10.1097/WCO.0000000000000329. Review. Hedström AK, Mowry EM, Gianfrancesco MA, Shao X, Schaefer CA, Shen L, Olsson T, Barcellos LF, Alfredsson L. J Neurol Neurosurg Psychiatry. 2016 May;87(5):454-60. doi: 10.1136/jnnp-2015-312176. Epub 2016 Mar 3. Smoking is a major preventable risk factor for multiple sclerosis. Hedström AK, Olsson T, Alfredsson L. Mult Scler. 2016 Jul;22(8):1021-6. doi: 10.1177/1352458515609794. Epub 2015 Oct 12 Body mass index during adolescence, rather than childhood, is critical in determining MS risk. Hedström AK, Olsson T, Alfredsson L. Mult Scler. 2016 Jun;22(7):878-83. doi: 10.1177/1352458515603798. Epub 2015 Sep 11. Anoctamin 2 identified as an autoimmune target in multiple sclerosis. Ayoglu B, Mitsios N, Kockum I, Khademi M, Zandian A, Sjöberg R, Forsström B, Bredenberg J, Lima Bomfim I, Holmgren E, Grönlund H, Guerreiro-Cacais AO, Abdelmagid N, Uhlén M, Waterboer T, Alfredsson L, Mulder J, Schwenk JM, Olsson T, Nilsson P. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2188-93. doi: 10.1073/pnas.1518553113. Epub 2016 Feb 9. 2015 Effect of Smoking Cessation on Multiple Sclerosis Prognosis. Ramanujam R, Hedström AK, Manouchehrinia A, Alfredsson L, Olsson T, Bottai M, Hillert J. JAMA Neurol. 2015 Oct;72(10):1117-23. doi: 10.1001/jamaneurol.2015.1788 Class II HLA interactions modulate genetic risk for multiple sclerosis. Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA,Alfredsson L, Anderson CA, Attfield KE, Baranzini SE, Barrett J, Binder TM, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Lar Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J; International IBD Genetics Consortium (IIBDGC), Kockum I, Leslie S, Lill CM, Martinelli-Boneschi F, Oksenberg JR, Olsson T, Oturai A, Saarela J, Søndergaard HB, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines JL, Pericak-Vance MA, Spencer CC, Stewart G, Hafler DA, Ivinson AJ, Harbo HF, Hauser SL, De Jager PL, Compston A, McCauley JL, Sawcer S, McVean G; International Multiple Sclerosis Genetics Consortium. Nat Genet. 2015 Oct;47(10):1107-13. doi: 10.1038/ng.3395. Epub 2015 Sep 7. Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort. Westerlind H, Imrell K, Ramanujam R, Myhr KM, Celius EG, Harbo HF, Oturai AB, Hamsten A,Alfredsson L, Olsson T, Kockum I, Koski T, Hillert J. Eur J Hum Genet. 2015 May;23(5):688-92. doi: 10.1038/ejhg.2014.155. Epub 2014 Aug 27 Frisell T, Forsberg L, Nordin N, Kiesel C, Alfredsson L, Askling J,Hillert J, Olsson T, Piehl F. Mult Scler. 2015 Apr 28. pii: 1352458515579216. [Epub ahead of print] Genetic variants are major determinants of CSF antibody levels in multiple sclerosis. Goris A, Pauwels I, Gustavsen MW, van Son B, Hilven K, Bos SD, Celius EG, Berg-Hansen P, Aarseth J, Myhr KM, D'Alfonso S, Barizzone N, Leone MA, Martinelli Boneschi F, Sorosina M, Liberatore G, Kockum I, Olsson T, Hillert J, Alfredsson L, Bedri SK, Hemmer B, Buck D, Berthele A, Knier B, Biberacher V, van Pesch V, Sindic C, Bang Oturai A, Søndergaard HB, Sellebjerg F, Jensen PE, Comabella M, Montalban X, Pérez-Boza J, Malhotra S, Lechner-Scott J, Broadley S, Slee M, Taylor B, Kermode AG, Gourraud PA; International Multiple Sclerosis Genetics Consortium, Sawcer SJ, Andreassen BK, Dubois B, Harbo HF. Brain. 2015 Mar;138(Pt 3):632-43. doi: 10.1093/brain/awu405. Epub 2015 Jan 22 Obesity interacts with infectious mononucleosis in risk of multiple sclerosis. Hedström AK, Lima Bomfim I, Hillert J, Olsson T, Alfredsson L. Eur J Neurol. 2015 Mar;22(3):578-e38. doi: 10.1111/ene.12620. Epub 2014 Dec 20. Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort. Westerlind H, Imrell K, Ramanujam R, Myhr KM, Celius EG, Harbo HF, Oturai AB, Hamsten A, Alfredsson L, Olsson T, Kockum I, Koski T, Hillert J. Eur J Hum Genet. 2015 May;23(5):688-92. doi: 10.1038/ejhg.2014.155. Epub 2014 Aug 27. 2014Gustavsen MW, Viken MK, Celius EG, Berge T, Mero IL, Berg-Hansen P, Aarseth JH, Myhr KM, Søndergaard HB, Sellebjerg F, Oturai AB, Hillert J, Alfredsson L, Olsson T, Kockum I, Lie BA, Harbo HF. J Neuroimmunol. 2014 Sep 15;274(1-2):174-9. doi: 10.1016/j.jneuroim.2014.06.024. Epub 2014 Jul 6. Engdahl E, Gustavsson R, Ramanujam R, Sundqvist E, Olsson T, Hillert J, Alfredsson L, Kockum I, Fogdell-Hahn A. Hum Immunol. 2014 Jun. Epub 2014 Mar 22. Variability in the CIITA gene interacts with HLA in multiple sclerosis. Gyllenberg A, Piehl F, Alfredsson L, Hillert J, Bomfim IL, Padyukov L, Orho-Melander M, Lindholm E, Landin-Olsson M, Lernmark Å; Swedish Childhood Diabetes Study Group; Diabetes Incidence in Sweden Study Group, Olsson T, Kockum I. Genes Immun. 2014 Apr-May;15(3):162-7. doi: 10.1038/gene.2013.71. Epub 2014 Jan 16. JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants. Sundqvist E, Buck D, Warnke C, Albrecht E, Gieger C, Khademi M, Lima Bomfim I, Fogdell-Hanh A, Link J, Alfredsson L, Sødergaard HB, Hillert J; International Multiple Sclerosis Genetics Consortium, Oturai AB, Hemme B, Kockum I, Olsson T. PLoS Pathog. 2014 April 24. Smoking and risk of treatment-induced neutralizing antibodies to interferon β-1a. Hedström AK, Ryner M, Fink K, Fogdell-Hahn A, Alfredsson L, Olsson T, Hillert J. Mult Scler. 2014 Apr. Epub Aug 7. Smoking and risk of multiple sclerosis: Evidence of modification by NAT1 variants. Briggs FB, Acuna B, Shen L, Ramsay P, Quach H, Bernstein A, Bellesis KH, Kockum I, Hedström AK, Alfredsson L, Olsson T, Schaefer C, Barcellos LF. Epidemiology. 2014 Mar 12. [Epub ahead of print] Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis. Hedström AK, Lima Bomfim I, Barcellos L, Gianfrancesco M, Schaefer C, Kockum I, Olsson T, Alfredsson L. Neurology. 2014 Mar 11. Epub 2014 Feb 5. Alcohol as a modifiable lifestyle factor affecting multiple sclerosis risk. Hedström AK, Hillert J, Olsson T, Alfredsson L. JAMA Neurol. 2014 Mar. Epub 2014 Jan 6. 2013Smokers run increased risk of developing anti-natalizumab antibodies. Hedström A, Alfredsson L, Lundkvist Ryner M, Fogdell-Hahn A, Hillert J, Olsson T. Mult Scler. 2013 Dec 5. [Epub ahead of print] Smoking and multiple sclerosis susceptibility. Hedström AK, Hillert J, Olsson T, Alfredsson L. Eur J Epidemiol. 2013 Nov. Epub 2013 Oct 22. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. International Multiple Sclerosis Genetics Consortium (IMSGC), Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, etal. Nat Genet. 2013 Nov. Epub 2013 Sep 29. Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort. Olsson T, Achiron A, Alfredsson L, Berger T, Brassat D, Chan A, Comi G, Eraksoy M, Hegen H, Hillert J, Jensen PE, Mirola L, Myhr KM, Oturai A, Schippling S, Siva A, Sorensen PS, Trampe AK, Weber T, Potts J, Plavina T, Paes D, Subramanyam M, Wiendl H, Dib H, Uren D, Hemmer B, Buck D. Mult Scler. 2013 Oct Epub 2013 Mar 4. A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis. Mechelli R, Umeton R, Policano C, Annibali V, Coarelli G, Ricigliano VA, Vittori D, Fornasiero A, Buscarinu MC; International Multiple Sclerosis Genetics Consortium; Wellvome Trust Case Control Consortium,2, Romano S, Salvetti M, Ristori G. PLoS One. 2013 May 16. Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity. Lundström W, Highfill S, Walsh ST, Beq S, Morse E, Kockum I, Alfredsson L, Olsson T; Hillert J, Mackall CL. Proc Natl Acad Sci U S A. 2013 May 7. Epub 2013 Apr 22. Fatty fish intake is associated with decreased occurrence of multiple sclerosis. Bäärnhielm M, Olsson T, Alfredsson L. Mult Scler. 2014 May. Epub 2013 Oct 24 Smoking and risk of treatment-induced neutralizing antibodies to interferon β-1a. Hedström AK, Ryner M, Fink K, Fogdell-Hahn A, Alfredsson L, Olsson T, Hillert J. Mult Scler. 2014 Apr. Epub Aug 7. Reverse causality behind the association between reproductive history and MS. Hedström A, Hillert J, Olsson T, Alfredsson L. Mult Scler. 2013 Jul 25. [Epub ahead of print] Nicotine might have a protective effect in the etiology of multiple sclerosis. Hedström AK, Hillert J, Olsson T, Alfredsson L. Mult Scler. 2013 Jul;19(8):1009-13. doi: 10.1177/1352458512471879. Epub 2013 Jan 14. Exposure to anaesthetic agents does not affect multiple sclerosis risk. Hedström AK, Hillert J, Olsson T, Alfredsson L. Eur J Neurol. 2013 May;20(5):735-9. doi: 10.1111/ene.12098. Epub 2013 Jan 24. Mero IL, Gustavsen MW, Sæther HS, Flåm ST, Berg-Hansen P, Søndergaard HB, Jensen PE, Berge T, Bjølgerud A, Muggerud A, Aarseth JH; INternational Multiple Sclerosis Genetic Consortium, Myhr KM, Celius EG, Sellebjerg F, Hillert J, Alfredsson L, Olsson T, Oturai AB, Kockum I, Lie BA, Andreassen BK, Harbo HF. PLoS One. 2013. Epub 2013 Mar 5. 2012Malmeström C, Gillett A, Jernås M, Khademi M, Axelsson M, Kockum I, Mattsson N, Zetterberg H, Blennow K, Alfredsson L, Wadenvik H, Lycke J, Olsson T, Olsson B. Mult Scler. 2013 Jun;19(7):871-6. doi: 10.1177/1352458512463766. Epub 2012 Oct 4. Lack of replication of interaction between EBNA1 IgG and smoking in risk for multiple sclerosis. Sundqvist E, Sundström P, Lindén M, Hedström AK, Aloisi F, Hillert J, Kockum I, Alfredsson L, Olsson T. Neurology. 2012 Sep 25;79(13):1363-8. Epub 2012 Aug 29. Link J, Kockum I, Lorentzen AR, Lie BA, Celius EG, Westerlind H, Schaffer M, Alfredsson L, Olsson T, Brynedal B, Harbo HF, Hillert J. PLoS One. 2012;7(5):e36779. Epub 2012 May 7 Hedström AK, Olsson T, Alfredsson L. Mult Scler. 2012 Sep;18(9):1334-6. doi: 10.1177/1352458512436596. Epub 2012 Feb 10. Bäärnhielm M, Hedström AK, Kockum I, Sundqvist E, Gustafsson SA, Hillert J, Olsson T, Alfredsson L. Eur J Neurol. 2012 Jul;19(7):955-62. doi: 10.1111/j.1468-1331.2011.03650.x. Epub 2012 Jan 31. 2011Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis. Hedström AK, Sundqvist E, Bäärnhielm M, Nordin N, Hillert J, Kockum I, Olsson T, Alfredsson L. Brain. 2011 Mar;134(Pt 3):653-64. Epub 2011 Feb 8 Exposure to environmental tobacco smoke is associated with increased risk for multiple sclerosis. Hedström AK, Bäärnhielm M, Olsson T, Alfredsson L. Mult Scler. 2011 Jul;17(7):788-93. Epub 2011 Mar 3. International Multiple Sclerosis Genetics Consortium. PLoS One. 2011 Apr 28;6(4):e18813. Epstein-Barr virus and multiple sclerosis: interaction with HLA. Sundqvist E, Sundström P, Lindén M, Hedström AK, Aloisi F, Hillert J, Kockum I, Alfredsson L, Olsson T. Genes Immun. 2012 Jan;13(1):14-20. doi: 10.1038/gene.2011.42. Epub 2011 Jul 21. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. International Multiple Sclerosis Genetics Consortium; Wellcome Trust Case Control Consortium 2, Sawcer S, Hellenthal G, Pirinen M et al Nature. 2011 Aug 10;476(7359):214-9. doi: 10.1038/nature102 No evidence of IL21 association with multiple sclerosis in a Swedish population. Lindén M, Nohra R, Sundqvist E, Khademi M, Hillert J, Alfredsson L, Olsson T, Kockum I. Tissue Antigens. 2011 Oct;78(4):271-4. doi: 10.1111/j.1399-0039.2011.01734.x. Epub 2011 Jul 8. Shift work at young age is associated with increased risk for multiple sclerosis. Hedström AK, Åkerstedt T, Hillert J, Olsson T, Alfredsson L. Ann Neurol. 2011 Nov;70(5):733-41. doi: 10.1002/ana.22597. Epub 2011 Oct 17. 2010RGMA and IL21R show association with experimental inflammation and multiple sclerosis. Nohra R, Beyeen AD, Guo JP, Khademi M, Sundqvist E, Hedreul MT, Sellebjerg F, Smestad C, Oturai AB, Harbo HF, Wallström E, Hillert J, Alfredsson L, Kockum I, Jagodic M, Lorentzen J, Olsson T. Genes Immun. 2010 Jun;11(4):279-93. Epub 2010 Jan 14. IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci. International Multiple Sclerosis Genetics Conssortium (IMSGC). Genes Immun. 2010 Jul;11(5):397-405. Epub 2010 Jun 17. Confirmation of association between multiple sclerosis and CYP27B1. Sundqvist E, Bäärnhielm M, Alfredsson L, Hillert J, Olsson T, Kockum I. Eur J Hum Genet. 2010 Dec;18(12):1349-52. Epub 2010 Jul 21. 2009Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis. Hedström AK, Bäärnhielm M, Olsson T, Alfredsson L. Neurology. 2009 Sep 1;73(9):696-701. HLA-DRB1 and month of birth in multiple sclerosis. Ramagopalan SV, Link J, Byrnes JK, Dyment DA, Giovannoni G, Hintzen RQ, Sundqvist E, Kockum I, Smestad C, Lie BA, Harbo HF, Padyukov L, Alfredsson L, Olsson T, Sadovnick AD, Hillert J, Ebers GC. Neurology. 2009 Dec 15;73(24):2107-11.
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